Vaginal estrogen cream. $50 for the whole year.
One clinical review. One prescription that is good for a full year. No subscription, no membership, no monthly charge — and your insurance may cover the medication itself.
Insurance may cover estradiol · Adults 18+ · You are not charged until your prescription is approved
Pay once. Not every month.
$50 one-time clinical fee. Your prescription is good for a full year of treatment. Fill it at the pharmacy you already use. Medication is billed separately by that pharmacy and paid directly to them — commonly around $13 per month.
There is no membership, no auto-renewing plan, and no card kept on file for recurring billing. When the year is up, you decide whether to renew.
Alloy, Winona, and comparable menopause telehealth services charge $40–$90 per month on recurring subscriptions, totaling $480–$1,000+ per year. Patients commonly save $270–$800 per year with us.
Pricing verified against major direct-to-consumer telehealth providers as of 2026.
Genitourinary syndrome of menopause.
Genitourinary syndrome of menopause (GSM) is the group of vaginal and urinary symptoms caused by declining estrogen around and after menopause. As estrogen levels drop, the vaginal and urinary tissues thin and lose elasticity. Local estrogen therapy restores those tissues directly, with minimal systemic absorption. It addresses symptoms that oral HRT often does not fully resolve.
Vaginal dryness
The most common menopausal complaint. Local estrogen restores moisture and elasticity within 2–4 weeks.
Painful intercourse
Vaginal thinning makes sex uncomfortable or painful (dyspareunia). Local estrogen restores tissue comfort.
Recurrent UTIs
Menopausal urinary changes increase UTI risk. Local estrogen reduces recurrence significantly.
Urgency & frequency
The urethra is also estrogen-sensitive. Local therapy often improves urinary symptoms.
FDA-approved estradiol. Usually covered by insurance.
We prescribe commercially available, FDA-approved vaginal estradiol cream — the standard first-line treatment. It is stocked at ordinary retail pharmacies, so you fill it wherever you already go.
Estradiol cream 0.01%
FDA-approved estradiol vaginal cream, supplied in 30g tubes. Most insurance plans cover this option with a copay. The standard first-line choice for most patients.
about $13.21/mo
cash price at Cost Plus Drugs — no insurance needed
With insurance you pay your copay instead. Copays commonly run $10–$100/mo, so use insurance only if yours is lower than the cash price.
The $50 clinical fee is separate from medication cost and is not billed to insurance. Pharmacy pricing varies by plan, pharmacy, and location; the figures above are estimates, not quotes.
Online intake. Clinician review. Prescription sent.
No appointment, no video call, no waiting room. You complete the intake whenever it suits you.
Online intake
A secure questionnaire covering medical history, menopausal status, medications, and any history of breast cancer or thromboembolic disease. Takes 5–10 minutes.
Clinician review
A licensed clinician reviews your intake for safety and confirms the treatment is appropriate for you. Typically 1–2 business days.
Prescription sent
Sent electronically to the pharmacy you choose. You pay the pharmacy directly for the medication, separately from the $50 clinical fee.
Every intake is reviewed by a licensed clinician.
Kim Wohlwend, MSN, APRN, is a dual ANCC board-certified Family and Psychiatric-Mental Health Nurse Practitioner. She personally reviews each intake and makes the prescribing decision. There is no algorithm and no automatic approval.
This service is operated by Midwest Mind & Body Healthcare, a practice based in Papillion, Nebraska, providing telehealth across 16 states.
- MSN, APRN
- ANCC Board Certified FNP
- ANCC Board Certified PMHNP
- Licensed in 16 states
Before starting vaginal estrogen, please read.
Safety & contraindications
Local vaginal estrogen has minimal systemic absorption and is considered safer than oral estrogen for most patients. However, we do not prescribe if you have a current or recent history of breast cancer, estrogen-sensitive cancer, active thromboembolic disease, or undiagnosed vaginal bleeding without OB-GYN clearance first.
- Pregnancy and breastfeeding. Vaginal estrogen therapy is generally not used during pregnancy or breastfeeding. Tell us before starting if you are pregnant, could be pregnant, trying to conceive, or breastfeeding.
- Personal and family history. Tell us about any personal history of breast cancer, endometrial cancer, undiagnosed vaginal bleeding, active thromboembolic disorders, liver disease, or known hypersensitivity. We will review whether vaginal estrogen is appropriate for you.
- FDA-approved medication only. We prescribe commercially available, FDA-approved vaginal estradiol where clinically appropriate. We do not prescribe compounded vaginal estrogen through this service.
- Systemic absorption. Vaginal estrogen has much lower systemic absorption than oral or transdermal estrogen, but absorption is not zero. Tell us about any history of estrogen-sensitive cancer or other conditions affected by estrogen.
Treatment is not guaranteed. Prescriptions are issued only when clinically appropriate, at the discretion of the reviewing clinician. This website does not provide medical advice.
Vaginal estrogen, answered.
Ready to start? It takes about 5 minutes.
$50 once for the year. No subscription. Insurance may cover the medication. Available to adults 18+ in 16 states.